University Staff

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Dr. Mingo M.H. YUNG (容銘浩博士)

Post-doctoral Fellow
Bsc; MPhil (PolyU); PhD (HK)
  • location
    Laboratory Block, Faculty of Medicine Building, 21 Sassoon Road
  • telephone
    (852) 3917 9375

Publications

2019
  • Sun J, Cai X, YUNG MMH, Zhou W, Li J, Zhang Y, Li Z, Liu SS, Cheung AN, Ngan HYS, Li Y, Dai Z, Kai Y, Tzatsos A, Peng W, Chan DW*, Zhu W*. miR-137 mediates the functional link between c-Myc and EZH2 that regulates cisplatin resistance in ovarian cancer. Oncogene 2019 Jan;38(4):564-580. (* Co-corresponding author)

2018
  • Zhou W., Sun W., Yung M.H., Dai S., Cai Y., Chen C.W., Meng Y., Lee J.B., Braisted J.C., Xu Y., Southall N.T., Shinn P., Huang X., Song Z., Chen X., Kai Y., Cai X., Li Z., Hao Q., Cheung A.N.Y., Ngan H.Y.S., Liu S., Barak S., Hao J., Dai Z., Tzatsos A., Peng W., Pei H., Han Z., Chan D.W., Zheng W. and Zhu W., Autocrine activation of JAK2 by IL-11 promotes platinum drug resistance, Oncogene. 2018. http://dx.doi.org/10.1038/s41388-018-0238-8 (Publication No. : 284933)

  • Yung M.H., Tang W.M., Cai C.H., Leung T.H.Y., Ngu S.F., Chan K.K.L., Xu D., Yang H.U.I.J.U.A.N., Ngan H.Y.S. and Chan D.W., GRO-α and IL-8 enhance ovarian cancer metastatic potential via the CXCR2-mediated TAK1/NFκB signaling cascade, Theranostics. 2018, 8: 1270-1285. http://dx.doi.org/10.7150/thno.22536 (Publication No. : 284377)

  • Sun J., Cai X., Yung M.H., Zhou W., Li J., Zhang Y., Li Z., Liu S., Cheung A.N.Y., Ngan H.Y.S., Li Y., Dai Z., Kai Y., Tzatsos A., Peng W., Chan D.W. and Zhu W., miR-137 mediates the functional link between c-Myc and EZH2 that regulates cisplatin resistance in ovarian cancer, Oncogene. Springer Nature Limited, 2018. http://dx.doi.org/10.1038/s41388-018-0459-x (Publication No. : 290017)

  • LEUNG L.L., Yung M.H., Ngan H.Y.S. and Chan D.W., Study of hedgehog signaling in cervical cancer, ESMO Open. BMJ, 2018, 3: A89-A89. http://dx.doi.org/10.1136/esmoopen-2018-EACR25.214 (Publication No. : 295865)

  • CHEN K., Liu X., MAK S.L., Yung M.H., Leung T.H.Y., Xu D., Ngu S.F., Chan K.K.L., Yang H.J., Ngan H.Y.S. and Chan D.W., Methylation-associated silencing of miR-193a-3p promotes ovarian cancer aggressiveness by targeting GRB7 and MAPK/ERK pathways , Theranostics. 2018, 8: 423-436. http://dx.doi.org/10.7150/thno.22377 (Publication No. : 284013)

2017
  • Mak CS, Yung MMH, Hui LMN, Leung LL, Liang R, Chen KM, Liu SS, Qin Y, Leung THY,  Lee KF, Chan KKL, Ngan HYS and Chan DW*  Dysregulation of miR-141/KLF12/Sp1/survivin signaling promotes anoikis resistance in ovarian cancer metastatic progression. Mol Cancer 2017 16(1):1-17.

  • Chan D.W., Hui W.W., Wang J.J., Yung M.H., Hui M.N., Qin Y.I.M.I.N.G., LIANG R., Leung T.H.Y., Xu D., Chan K.K.L., Yao K.M., Tsang B.K. and Ngan HYS, DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-β/SMAD4 signaling, Oncogene. 2017 Mar;36(10):1404-1416.

  • Mak CS, Yung MM, Hui LM, Leung LL, Liang R, Chen K, Liu SS, Qin Y, Leung TH, Lee KF, Chan KK, Ngan HY, Chan DW. MicroRNA-141 enhances anoikis resistance in metastatic progression of ovarian cancer through targeting KLF12/Sp1/survivin axis. Mol Cancer. 2017 Jan 17;16(1):11. doi: 10.1186/s12943-017-0582-2.

2016
  • Chan D.W., Hui W.W., Wang J.J., Yung M.H., Hui M.N., Qin Y.I.M.I.N.G., LIANG R., Leung T.H.Y., Xu D., Chan K.K.L., Yao K.M., Tsang B.K. and Ngan H.Y.S., DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-β/SMAD4 signaling, In: Drs. Douglas Green and Justin Stebbing , Oncogene. UK, Macmillan Publishers Limited, 2016, 36: 1404-1416.

  • Yung MH, Ross FA, Hardie DG, Leung TH, Zhan JB, Ngan HYSand Chan DW*.  Bitter melon (Momordica charantia) extract functions as a natural AMPK activator and synergistically enhances cisplatin cytotoxicity in ovarian cancer cells. Integrat Cancer Ther. 2016 15(3):376-89. (The most read paper in 2015/16) * (Corresponding author)

  • Yung MH, Ngan HYS and Chan DW*.  Targeting AMPK signaling in combating ovarian cancers: Opportunities and Challenges. Acta Biochimica et Biophysica Sinica. 2016 48(4):301-17.