University Staff

Dr. Raymond H.W. LI hong kong university logo queen mary hosipital logo

Dr. Raymond H.W. LI (李幸奐醫生)

Clinical Associate Professor
MBBS; MMedSc (HK); FRCOG; FHKAM (O&G); Cert RCOG (Reproductive Medicine); Cert HKCOG (Reproductive Medicine)
  • location
    6/F, Professorial Block, Queen Mary Hospital
  • telephone
    (852)-2255-4684
  • facsimile
    (852)-2855-0947
  • raymondli@hku.hk
  • HKU Scholars Hub
Research Interests
  • Clinical applications of anti-Mullerian hormone
  • Ulipristal and emergency contraception
  • Metabolic and endocrine aspects of polycystic ovary syndrome
  • Adrenomedullin and tubal ectopic pregnancy

Publications

2017
  • Li HWR, Li YX, Li TT, Fan H, Ng EH, Yeung WS, Ho PC, Lee KF. Effect of ulipristal acetate and mifepristone at emergency contraception dose on the embryo-endometrial attachment using an in vitro human trophoblastic spheroid and endometrial cell co-culture model. Hum Reprod. 2017 Dec 1;32(12):2414-2422. doi: 10.1093/humrep/dex328.

2015
  • Yeung TWY, Chai J, Li RHW, Lee VCY, Ho PC and Ng EHY. Reply: Endometrial injury and reproductive outcomes: there's more to this story than meets the horse's blind eye. Human Reproduction 2015, 3: 749-750.

  • Wan HLT, Hui PW, Li RHW and Ng EHY. Obstetric outcomes in women with polycystic ovary syndrome and isolated polycystic ovaries undergoing in vitro fertilization: a retrospective cohort analysis. Journal of Maternal and Fetal Neonatal Medicine 2015, 28: 475-478.

  • Li RHW, Lam KSL, Tam S, Lee VCY, Yeung TWY, Cheung PT, Yeung WSB, Ho PC and Ng EHY. Screening for dysglycaemia by oral glucose tolerance test should be recommended in all women with polycystic ovary syndrome. Human Reproduction 2015, 30(9): 2178-2183.

  • Lam KW, Li RHW, Ng EHY, Ho PC and Yeung WSB., Semen analysis - what a clinician should know. Journal of Paediatrics, Obstetrics and Gynaecology Singapore 2015, Jan: 37-44.

  • Ko JK, Li RH, Cheung VY. Two-dimensional versus three-dimensional laparoscopy: evaluation of physicians' performance and preference using a pelvic trainer. Journal of minimally invasive gynecology 2015;22(3):421-7.

  • Chai J, Lee VCY, Yeung TW., Li RHW, Ho PC and Ng EHY Live birth and cumulative live birth rates in expected poor ovarian responders defined by the Bologna criteria following IVF/ICSI treatment. PLoS One 2015 Mar 6;10(3):e0119149.

  • Ko JK, Li RH, Cheung VY. Caesarean scar pregnancy: a 10-year experience. The Australian & New Zealand journal of obstetrics & gynaecology. 2015;55(1):64-9.

  • Li HW, Liao SB, Chiu PC, Yeung WS, Ng EH, Cheung AN, Tang F, O WS. Effects of adrenomedullin on the expression of inflammatory cytokines and chemokines in oviducts from women with tubal ectopic pregnancy: an in-vitro experimental study. Reprod Biol Endocrinol. 2015 Nov 5;13(1):120. [Medline]

  • So KH, Kodithuwakku SP, Kottawatta KS, Li RH, Chiu PC, Cheung AN, Ng EH, Yeung WS, Lee KF.Human chorionic gonadotropin stimulates spheroid attachment on fallopian tube epithelial cells through the mitogen-activated protein kinase pathway and down-regulation of olfactomedin-1. Fertil Steril. 2015 May 18. pii: S0015-0282(15)00304-0. doi: 10.1016/j.fertnstert.2015.04.030. [Epub ahead of print]

2014
  • Seto MT, Yeung TWY, Li RHW, Ng EHY. Comparison of on-going pregnancy rates and multiple pregnancy rates of intrauterine insemination with ovarian stimulation using the clomiphene citrate versus gonadotrophin protocols. Hong Kong J Gynaecol Obstet Midwifery 2014; 14:89-92

  • Chai J, Yeung WYT, Lee VCY, Li RHW, Ho PC, Ng HYE. Live birth rates following in vitro fertilization in women with thyroid autoimmunity and/or subclinical hypothyroidism.  Clin Endocrinol (Oxf) 2014; 82(1): 122-127.

  • Yeung TWY, Chai J, Li RHW, Lee VCY, Ho PC, Ng EHY. The effect of endometrial injury on ongoing pregnancy rate in unselected subfertile women undergoing in vitro fertilization: a randomized controlled trial. Hum Reprod 2014; 29(11): 2474-2481.

  • Yeung TWY, Chai J, Li RHW, Lee VCY, Ho PC and Ng EHY. A randomized, controlled, pilot trial on the effect of dehydroepiandrosterone on ovarian response markers, ovarian response, and in vitro fertilization outcomes in poor responders. Fertility and Sterility 2014, 102: 108-115.e1.

  • Ng EHY, Li RHW, Chen L, Lan VT, Tuong HM, Quan S.  A randomized double blind comparison of atosiban in patients undergoing IVF treatment.  Hum Reprod 2014;29(12):2687-2694.

  • Lui MWE, Shek NWM, Li RHW, Chu SKF and Pun TC. Management of heterotopic cesarean scar pregnancy by repeated transvaginal ultrasonographic-guided aspiration with successful preservation of normal intrauterine pregnancy and complicated by arteriovenous malformation. European Journal of Obstetrics & Gynecology and Reproductive Biology. 2014, 175: 209-210.

  • Li RHW, Lo STS and Ho PC. Emergency contraception. Best Practice & Research Clinical Obstetrics & Gynaecology 2014, 28: 835-844.

  • Li RHW, Liao S., Yeung WSB, Ng EHY, O WS and Ho PC. Ulipristal acetate resembles mifepristone in modulating human Fallopian tube function. Human Reproduction 2014 29: 2156-2162.

  • Li RHW, Lee VCY, Lau EYL, Yeung WSB, Ho PC, Ng EHY. Ovarian response and cumulative live birth rate of women undergoing in-vitro fertilisation who had discordant anti-mullerian hormone and antral follicle count measurements: a retrospective study.  PLoS One 014;9(10):e108493.

  • Li RHW, Lee VCY, Lau EYL, Yeung WSB, Ho PC and Ng EHY. Role of baseline antral follicle count and anti-Mullerian hormone in the index stimulation cycle of IVF treatment in predicting outcome of subsequent frozen-thawed embryo transfers. Gynecological Endocrinology 2014 30: 490-493.

  • Li RHW, Lee VCY, Lau EYL, Yeung WSB, Ho PC and Ng EHY. Cumulative live-birth rate in women with polycystic ovary syndrome or isolated polycystic ovaries undergoing in-vitro fertilisation treatment. Journal of Assisted Reproduction and Genetics 2014, 31: 205-211.

  • Li RHW, Lee VCY, Ho PC and Ng EHY. Ovarian sensitivity index is a better measure of ovarian responsiveness to gonadotrophin stimulation than the number of oocytes during in-vitro fertilization treatment. Journal of Assisted Reproduction and Genetics 2014, 31: 199-203.

  • Lee VCY, Li RHW, Chai J, Yeung TWY, Yeung WSB, Ho PC and Ng EHY. Effect of preovulatory progesterone elevation and duration of progesterone elevation on the pregnancy rate of frozen–thawed embryo transfer in natural cycles. Fertility and Sterility 2014, 101: 1288-1293.

  • Ko JKY, Huang VW, Li RHW, Yeung WSB, Ho PC and Chiu CN. An in vitro study of the effect of mifepristone and ulipristal acetate on human sperm functions. Andrology 2014;2(6):868-874.

  • Chai J, Yeung TWY, Lee VCY, Li RHW, Lau EYL, Yeung WSB, Ho PC and Ng EHY. Live birth rate, multiple pregnancy rate, and obstetric outcomes of elective single and double embryo transfers: Hong Kong experience. Hong Kong Medical Journal 2014, 20(2):102-106.

  • Li HW, Liao SB, Yeung WS, Ng EH, O WS, Ho PC. Ulipristal acetate resembles mifepristone in modulating human Fallopian tube function.Hum Reprod. 2014 Aug 19. pii: deu210. [Epub ahead of print]

  • Chai J, Yeung WY, Lee CY, Li HW, Ho PC, Ng HY. Live birth rates following in vitro fertilization in women with thyroid autoimmunity and/or subclinical hypothyroidism. Clin Endocrinol (Oxf). 2014 Jan;80(1):122-7. [PubMed]

2013
  • Chung BH, Luk HM, Lo IF, Lam ST, Li RH. A second report of p.Pro986Leu variant in COL2A1-phenotypic overlap with SEDC and other forms of type II collagenopathies. Am J Med Genet A. 2013 Apr;161A(4):918-20. [Medline]

  • Lee VC, Li RH, Ng EH, Yeung WS, Ho PC. Luteal phase support does not improve the clinical pregnancy rate of natural cycle frozen-thawed embryo transfer: a retrospective analysis. Eur J Obstet Gynecol Reprod Biol. 2013 Jul;169(1):50-3. [PubMed]

  • Li HW, Lee VC, Lau EY, Yeung WS, Ho PC, Ng EH. Role of baseline antral follicle count and anti-Mullerian hormone in prediction of cumulative live birth in the first in vitro fertilisation cycle: a retrospective cohort analysis. PLoS One. 2013 Apr 23;8(4):e61095. [PubMed]

  • O WS, Li HWR, Liao SB, Cheung ANY, Ng EHY, Yeung WSB, Ho JC, Tang F. The decreases in adrenomedullin and ciliary beat frequency in the nasal epithelium in tubal pregnancy Fertil Steril (2013 Aug;100(2):459-463 [PubMed]

  • Yeung TW, Li RH, Lee VC, Ho PC, Ng EH. A randomized double-blinded placebo-controlled trial on the effect of dehydroepiandrosterone for 16 weeks on ovarian response markers in women with primary ovarian insufficiency. J Clin Endocrinol Metab. 2013 Jan;98(1):380-8. [PubMed]

2012
  • Li HW, Ng EH, Wong BP, Anderson RA, Ho PC, Yeung WS. Correlation between three assay systems for anti-Müllerian hormone (AMH) determination. J Assist Reprod Genet. 2012 Dec;29(12):1443-6.

  • Liao SB, Li HW, Ho JC, Yeung WS, Ng EH, Cheung AN, Tang F, O WS. Possible role of adrenomedullin in the pathogenesis of tubal ectopic pregnancy. J Clin Endocrinol Metab. 2012 Jun;97(6):2105-12. [PubMed]

  • Yeung TWY, Lee CYV, Li HWR, Ng EHY. HKCOG guidelines: induction of ovulation. Journal of Paediatrics, Obstetrics and Gynaecology 2012;Jan/Feb, 5-31.

2011
  • Lee VC, Yung SS, Li RH, Watzer B, Schweer H, Ng EH, Ho PC. A randomized comparison of pharmacokinetics of a single vaginal dose of dry misoprostol or misoprostol moistened with normal saline or with acetic acid. Hum Reprod. 2011 Nov;26(11):2981-7. [PubMed]

  • Li HWR, Yeung WSB, Lau EY, Ho PC, Ng EHY. Evaluating the performance of serum antimullerian hormone concentration in predicting the live birth rate of controlled ovarian stimulation and intrauterine insemination. Fertil Steril. 2010;94:2177-81. [PubMed]

  • Li RHW, Anderson RA, Yeung WS, Ho PC, Ng EH. Evaluation of serum antimullerian hormone and inhibin B concentrations in the differential diagnosis of secondary oligoamenorrhea. Fertil Steril. 2011 Sep;96(3):774-9. [PubMed]

  • Li RHW, Brereton RE, Anderson RA, Ho CKM.  Vitamin D deficiency is common and associated with metabolic risk factors in patients with polycystic ovary syndrome.  Metabolism 2011;60:1475-1481.

  • Li RHW, Gebbie AE, Wong RWS, Ng EHY, Glasier AF, Ho PC. The use of sex hormones in women with rheumatological diseases. Hong Kong Med J 2011;17(6):487-491.

  • Li RHW, Lo SST, Ng EHY, Ho PC. An update on emergency contraception. J Paediat, Obst & Gyna 2011;36:81-88.

  • Li RHW, Ng EHY, Ho PC. Handbook on Managing Infertility (Meeting the Challenges in Low-Resource Settings) - Asia and Oceania Federation of Obstetrics and Gynaecology. Polycystic Ovary Syndrome and Infertility 2011;11:105-111.

  • Li RHW, Wong GCY, Yeung WSB, Ho PC, Ng EHY. Serum anti-mullerian hormone level is not altered in women using hormonal contraceptives. Contraception 2011;83:582-585.

2010
  • Kini S, Li HWR, Morrell D, Pickering S, Thong KJ.  Anti-mullerian hormone and cumulative pregnancy outcome in in-vitro fertilization.  J Assist Reprod Genet 2010;27:449-456.

  • Li HWR, Anderson RA. Recent advances in hormonal contraception. F1000 Med Rep 2010;2:58.

  • Li HWR, Hui PW, Tang MHY, Lau ET, Yeung WSB, Ho PC, Ng EHY. Maternal serum anti-Mullerian hormone level is not superior to chronological age in predicting Down syndrome pregnancies. Prenat Diagn. 2010;30:320-4.

  • Li HWR, Liao S, Chiu PCN, Tam WW, Ho JCM, Ng EHY, Ho PC, Yeung WSB, Tang F, O WS, Expression of adrenomedullin in human oviduct, its regulaton by the hormonal cycle and contact with spermatozoa, and its effect on ciliary beat frequency of the oviductal epithelium, Journal of Clinical Endocrinology and Metabolism. 2010;95:E18-E25. (Publication No. : 182871) 

  • Li HWR, Ng EHY, Ho PC. Clinical applications of misoprostol in gynaecology.  J Paed Obstet Gynaecol 2010;36: 81-88.

  • Li HWR, van Esch M, de Vries J, Duncan WC, Anderson RA. Gonadotrophin ovulation induction is a successful treatment for World Health Organisation Group II Anovulatory Subfertility in women aged up to 40 and with body mass index up to 34. Hum Fertil 2010;13:35-40.

  • Yeung WS, Li RH, Cheung TM, Ng EH, Lau EY, Ho PC. Frozen-thawed embryo transfer cycles. Hong Kong Med J. 2009;15:420-6.

Research Grants
    • A longitudinal study of endocrine and metabolic parameters in Chinese women with polycystic ovary syndrome (Hong Kong Obstetrical and Gynaecological Trust Fund)
    • An in vitro study of endocrine factors regulating expression of anti-Mullerian hormone in human granulosa cells (Small Project Funding, HKU)
Professional activities
  • Honorary Medical Consultant, The Family Planning Association of Hong Kong
  • Secretary and Member, Reproductive Medicine Subspecialty Board, Hong Kong College of Obstetricians and Gynaecologists
  • Member, Working Group on Diploma of Community Gynaecology, Hong Kong College of Obstetricians and Gynaecologists.
  • Member, Guideline Subcommittee, Hong Kong College of Obstetricians and Gynaecologists.
  • Member, Manpower Subcommittee, Hong Kong College of Obstetricians and Gynaecologists.